Case Report

Anti-N-Methyl-D-Aspartate-Receptor Encephalitis in Young Females


  • Kamlesh Kumari
  • Neeru Sahni
  • Vimla Kumari
  • Vikas Saini

Received Date: 13.01.2017 Accepted Date: 17.04.2017 Turk J Anaesthesiol Reanim 2017;45(6):377-379

Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is an immune-mediated disease commonly associated with ovarian teratoma. Anti-NMDA–receptor autoantibodies disrupt NMDA function leading to the development of psychosis, seizures and autonomic dysfunction. The treatment includes underlying tumour resection and immunosuppression. Slow recovery and unpredictable clinical course makes intensive care management of these patients challenging. We report the management of two young female patients with anti-NMDA–receptor encephalitis associated with ovarian teratoma.

Keywords: NMDA, encephalitis, ovarian teratoma