Objective:
In this study we aimed to investigate the effects of bispectral index (BIS) and neuromuscular block monitoring on anaesthesia depth and recovery on cardiac patients, whom were scheduled to undergo open cholecystectomy operation under desflurane anaesthesia.
Methods:
After the approval of the Ethics Committee and consent of the patients, cases were divided into two groups. All patients received standard induction drugs, and 4-6% desflurane was used for maintenance of anaesthesia. In Group I, the anaesthesiologist was blind to BIS, and end-tidal volatile agent concentration (ETVAC) of desflurane was titrated according to the patients’ haemodynamic changes. In Group II, ETVAC of desflurane was titrated to maintain BIS at 50-60. The haemodynamic data, BIS values, end-tidal volatile agent concentration (ETVAC) and train of four (TOF) values were recorded at pre-induction, post-induction, post-intubation, 1st and 5th minutes after surgical incision and then every 15 min. At the end of the operation, extubation time and time to reach aldrete recovery score ≥9 were recorded in each groups. Additionally, neuromuscular agent and narcotic agent doses were recorded.
Results:
The BIS values were lower for Group I in all times, except preand post-induction times (p<0.05). ETVAC values of all times were lower for Group II (p<0.05).
Conclusion:
The requirement of volatile agent which was given according to BIS monitoring was lower than in the standard technique, but it is considered not to affect the early extubation, recovery and neuromuscular agent requirement dependent on TOF monitoring.
Keywords: Bispectral index, desflurane, anaesthesia, recovery period