Anti-N-Methyl-D-Aspartate-Receptor Encephalitis in Young Females
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Case Report
P: 377-379
December 2017

Anti-N-Methyl-D-Aspartate-Receptor Encephalitis in Young Females

Turk J Anaesthesiol Reanim 2017;45(6):377-379
1. Department of Anaesthesia and Intensive Care, Postgraduate Institute of Medical Education and Research, Chandigarh, India
2. Department of Gynaecology and Obstetric, Dr. S.N. Medical College Jodhpur, Rajasthan, India
No information available.
No information available
Received Date: 13.01.2017
Accepted Date: 17.04.2017
Publish Date: 15.09.2017
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ABSTRACT

Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is an immune-mediated disease commonly associated with ovarian teratoma. Anti-NMDA–receptor autoantibodies disrupt NMDA function leading to the development of psychosis, seizures and autonomic dysfunction. The treatment includes underlying tumour resection and immunosuppression. Slow recovery and unpredictable clinical course makes intensive care management of these patients challenging. We report the management of two young female patients with anti-NMDA–receptor encephalitis associated with ovarian teratoma.