Turkish Journal of Anaesthesiology & Reanimation

Comparison of Ropivacaine and Levobupivacaine in Supraclavicular Brachial Plexus Blocks-A Double Blinded Randomized Control Study


Department of Cardiac Anaesthesia, Sri Ramachandra Institute of Higher Education and Research, Chennai, India

Turk J Anaesthesiol Reanim 2021; 49: 278-283
DOI: 10.5152/TJAR.2021.266
Read: 320 Downloads: 147 Published: 09 August 2021

Background: Brachial plexus anaesthesia has been an indispensable tool in the anaesthesiologist’s armamentarium. Clinical studies have shown that levobupivacaine and ropivacaine have fewer adverse effects on the cardiovascular and central nervous system making them more advantageous in regional anaesthesia techniques. Less information is available regarding their comparable clinical data. Only a few studies have compared levobupivacaine and ropivacaine for brachial plexus blocks; hence, this study was aimed to compare the analgesic effectiveness and nerve block characteristics of ropivacaine and levobupivacaine in supraclavicular brachial plexus blocks in upper limb surgeries.

Methods: Patients with American Society of Anaesthesiologists physical status I or II coming for elective upper limb surgeries were included in the study. Total numbers of 62 patients were randomly allocated into two groups, group A and group B. Group A received 25mL of 0.75% ropivacaine, and group B received 25mL of 0.5% levobupivacaine. The duration of analgesia, onset of block, duration of sensory, and motor blockade were studied and compared.

Results: The mean duration of analgesia in group ropivacaine was 8.33 hours and in group levobupivacaine was 10.23 hours which was statistically significant. Ropivacaine had a faster sensory onset compared to levobupivacaine (5.22 vs. 6.88 minutes). The duration of sensory and motor blockade was longer with levobupivacaine than ropivacaine (sensory—8.64 vs. 10.29 hours, motor—8.32 vs. 9.8 hours).

Conclusion: Levobupivacaine had longer duration of analgesia. The sensory and motor blockade was also longer with levobupivacaine.

Cite this article as: Thalamati D, Sambandam KG, Kodali VRK, Karthekeyan RB, Vakamudi M. Comparison of Ropivacaine and Levobupivacaine in Supraclavicular Brachial Plexus Blocks-A Double Blinded Randomized Control Study. Turk J Anaesthesiol Reanim. 2021;49(4):278-283.

EISSN 2667-6370