Turkish Journal of Anaesthesiology & Reanimation
ORIGINAL ARTICLE

Comparison of Ventilator-Associated Pneumonia in Patients Admitted to Intensive Care for COVID-19 Versus Other Reasons: A Single-Centered Study

1.

Department of Anaesthesiology and Reanimation ICU, HSU Haydarpaşa Numune Training and Research Hospital, İstanbul, Turkey

2.

Department of Infectious Diseases and Clinical Microbiology, HSU Haydarpaşa Numune Training and Research Hospital, İstanbul, Turkey

3.

HSU Haydarpaşa Numune Training and Research Hospital Management, İstanbul, Turkey

Turk J Anaesthesiol Reanim 2022; 50: Supplement S22-S28
DOI: 10.5152/TJAR.2022.21310
Read: 646 Downloads: 110 Published: 13 June 2022

Objective: COVID-19 patients in intensive care usually need invasive mechanical ventilation due to advanced respiratory failure. Deep lym- phopenia, immunosuppressive agents, long-term mechanical ventilation, and sedation may lead to ventilator-associated pneumonia; an impor- tant cause of morbidity and mortality. This study evaluates the frequency, clinical features, causative pathogens, and outcomes of ventilator-asso ciated pneumonia in COVID-19 patients who require mechanical ventilation.

Methods: The files of patients hospitalized in our hospital’s intensive care clinic between March 25, 2020, and January 15, 2021, in the first 2 peaks due to COVID-19 and other reasons were retrospectively reviewed.

Results: We found ventilator-associated pneumonia rate in COVID-19 patients as 52.2%, which was statistically significantly higher than in non-COVID patients (33.5%). Purulent sputum, leukocyte, and procalcitonin levels were found to be significantly higher in both groups develop- ing ventilator-associated pneumonia. However, fever levels were found to be significantly normal in both groups; 97.1% and 87%, respectively. High fever was observed in only 2.9% of COVID-19 patients who developed ventilator-associated pneumonia. We determined a mortality rate of 17 (100%) in the diabetes patients in the COVID-19 group, which was statistically significantly higher than in non-COVID-19 patients at 9 (64.3%). The mortality rate (86.1%) in those with COVID-19 was statistically significantly higher than in those without COVID-19 (64.9%).

Conclusions: Ventilator-associated pneumonia is more common in COVID-19 patients treated with mechanical ventilation than in non- COVID patients. The predictive value of fever in the diagnosis is very low, and agent production together with increased purulent sputum will be more valuable in terms of diagnosis.

Cite this article as: Sarı A, Akça H, Akman D, İnan A, Kaymakçı A, Ekinci O. Comparison of ventilator-associated pneumonia in patients admitted to intensive care for COVID-19 versus other reasons: A single-centered study. Turk J Anaesthesiol Reanim. 2022;50(Suppl 1):S22-S28.

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