Turkish Journal of Anaesthesiology & Reanimation
CASE REPORT

Efficacy of Hyaluronidase in the Mannitol Extravasation Induced Compartment Syndrome-A Case Report and Review of Literature

1.

Department of Anesthesia & Critical Care, All India Institute of Medical Sciences (AIIMS), Jodhpur, India

2.

Department of Neurosurgery, All India Institute of Medical Sciences (AIIMS), Jodhpur, India

Turk J Anaesthesiol Reanim 2021; 49: 329-333
DOI: 10.5152/TJAR.2021.570
Read: 141 Downloads: 62 Published: 09 August 2021

Mannitol is one of the indispensable drugs in neurosurgery to manage the raised intracranial pressure. Though considered safe, extravasation of mannitol into the tissues can cause considerable morbidity with the consequent development of compartment syndrome. We report a case of a 50-year-old female who developed forearm compartment syndrome due to mannitol extravasation after undergoing surgery for frontal glioma under general anaesthesia. The severe forearm compartment syndrome could be successfully managed without fasciotomy using hyaluronidase. We describe the pathophysiology, prevention and treatment strategies emphasising the use of hyaluronidase in the management of mannitol extravasation induced compartment syndrome.

Cite this article as: Kaur M, Balakrishnan N, Gosal JS, Bhatia P, Bhaskar S, Jha DK. Efficacy of Hyaluronidase in the Mannitol Extravasation Induced Compartment Syndrome—A Case Report and Review of Literature. Turk J Anaesthesiol Reanim. 2021; 49(4):329-333.

Files
EISSN 2667-6370